T cell activation and function require a structured engagement of antigen-presenting cells. These cell contacts are characterized by two distinct dynamics in vivo: transient contacts resulting from promigratory junctions called…

Optimal protein synthesis requires bases in transfer RNAs to be modified. A key modification has been shown to involve an unusual two-step mechanism that entails the sequential activities of two…

Cancer incidence and mortality statistics reported by the American Cancer Society1 and other resources were used to create the list. To qualify as a common cancer for the list, the estimated…